Tacrolimus CAS NO.:104987-11-3
Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis. Tacrolimus is used to prevent rejection of organ transplants. Tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acute rejection after transplantation, but decreasing the toxin side effects.
Tests Specifications
Description A white or off-white crystalline powder
Identification IR and UV Spectrum
Specifications for Tacrolimus:
Tests Specifications
Description A white or off-white crystalline powder
Identification IR and UV Spectrum
Solubility Soluble in carbinol, alcohol, ethyl acetate, chloroform and diethyl ether,
and slightly soluble in n-hexyl alcohol and benzinum, but insoluble in water.
Heavy Metals ≤20ppm
Residue on ignition ≤0.2%
Total impurities ≤2.0%
Tautomers I+II ≤1.0%
Assay(HPLC) ≥98%